- Sears Roebuck & Co
- Seaton & Bowman Inc
- Second Selection
- Second Skin Taxidermy
- Second Time Around
- Security Systems Of America
- SEIU
- Semosky Heating & Air Cond
- Sensus Metering Sys
- Sentry Pest Control
- Sepic Orthodontic
- Seppfr-Sfru
- Seventh Day Adventist Hilltop
- Sew Special
- Shadyside Restaurant & Banquet
- Shake & Bake Entertainment
- Shamrock Carpets
- Shane Felter Industries
- Sharon C Stokes DDS
- Sharon Marian
- Sheetz
- Shelley's Auto Sales
- Shelly M Snoddy
- Sherwin-Williams Paints
